PubMed

• Utility of the US Preventive Services Task Force for Preeclampsia Risk Assessment and Aspirin Prophylaxis July 17, 2025
  CONCLUSIONS AND RELEVANCE: In this prospective cohort study of 5684 singleton pregnancies, 89% of the population was assessed as having increased risk (moderate or high) of preeclampsia by USPSTF criteria. These findings suggest that moderate risk factors in the absence of high risk factors show no or low value for estimating the risk of developing […]
  Thomas F McElrath
• The Chemical Exposome on Ovarian Aging in Adult Women: a Narrative Review June 30, 2025
  PURPOSE OF REVIEW: The effects of environmental exposures on female reproductive outcomes in early life are well studied. In contrast, we do not understand the broad range of chemical risk factors on women's reproductive physiology during midlife. The purpose of this review is to summarize the epidemiological literature on associations between environmental exposures (i.e., phthalates, […]
  Lauren M Petrick
• Cervicovaginal microbiome alters transcriptomic and epigenomic signatures across cervicovaginal epithelial barriers May 19, 2025
  CONCLUSIONS: These results provide new insights into host-microbe interactions within the lower reproductive tract and suggests that modulating the vaginal microbiome could offer innovative therapeutic strategies to improve reproductive health.
  Lauren Anton
• Correction to: Clinician-reported childbirth outcomes, patient-reported childbirth trauma, and risk for postpartum depression May 19, 2025
  No abstract
  Rebecca Waller
• Maternal Immune Activation During Pregnancy and Obstetric Outcomes: A Population-Based Cohort Study May 2, 2025
  CONCLUSIONS: We found no strong evidence of a link between early gestation typical inflammatory marker levels and the risk of adverse pregnancy outcomes.
  Frederieke A J Gigase
• Fatigue loading and volumetric microscopy demonstrate changes to the mouse cervix throughout and after pregnancy April 29, 2025
  INTRODUCTION: The cervix plays important mechanical roles in pregnancy and regulating the timing of parturition. Dysfunction of the cervix is implicated in disorders of parturition including spontaneous preterm birth, failed induction of labor and post term pregnancies. To address these disorders, it is imperative to first understand the function of the cervix throughout a normal […]
  Jeremy D Eekhoff
• Molecular subtyping of hypertensive disorders of pregnancy April 8, 2025
  Hypertensive disorders of pregnancy (HDP), including preeclampsia, affect 1 in 6 pregnancies, are major contributors to maternal morbidity and mortality, yet lack precision medicine strategies. Analyzing transcriptomic data from a prospectively-collected diverse cohort (n = 9102), this study reveals distinct RNA subtypes in maternal blood, reclassifying clinical HDP phenotypes like early/late-onset preeclampsia. The placental gene […]
  Michal A Elovitz
• Adverse Pregnancy Outcomes and N-Terminal Pro-Brain Natriuretic Peptide Levels 2 to 7 Years After Delivery: The nuMoM2b Heart Health Study April 2, 2025
  No abstract
  Priya M Freaney
• VIRGO2: Unveiling the Functional and Ecological Complexity of the Vaginal Microbiome with an Enhanced Non-Redundant Gene Catalog March 17, 2025
  Despite the importance of the cervicovaginal microbiome, the mechanisms that govern its composition and drive its impact on host physiology remain poorly understood. This study expands our understanding of the function and ecology of the vaginal microbiome using VIRGO2, an enhanced non-redundant gene catalog comprising over 1.7 million well-annotated genes from body-site specific microbes and […]
  M T France
• Trajectories of mHealth-Tracked Mental Health and Their Predictors in Female Chronic Pelvic Pain Disorders March 4, 2025
  CONCLUSION: These findings suggest that engaging in MVPA is beneficial to the mental health of females with CPPD. Additionally, this study demonstrates the potential of ambulatory mHealth-based data combined with functional models for delineating inter-individual and temporal variability.
  Emily L Leventhal
• Antibiotic exposure is associated with minimal gut microbiome perturbations in healthy term infants January 25, 2025
  CONCLUSIONS: Short-term and long-term gut microbiome perturbations by antibiotic exposure were detectable but substantially smaller than those associated with breastfeeding and infant age.
  Alain J Benitez
• Persistent Short Sleep Duration From Pregnancy to 2 to 7 Years After Delivery and Metabolic Health December 26, 2024
  CONCLUSIONS AND RELEVANCE: In this study, short sleep duration that persisted from pregnancy to 2 to 7 years after delivery was associated with a greater risk for adverse cardiometabolic outcomes. Future studies should explore whether sleep-targeted interventions during and after pregnancy are associated with improved cardiometabolic health outcomes, particularly among populations at increased risk.
  Minjee Kim
• Enhanced placental antibody transfer efficiency with longer interval between maternal respiratory syncytial virus vaccination and birth November 8, 2024
  CONCLUSION: Vaccine administration earlier in the approved 32 to 36 week window (at least 5 weeks prior to delivery) results in the highest transplacental transfer of maternal antibodies to the neonate. These results should inform the counseling of pregnant individuals on optimal vaccination timing.
  Olyvia J Jasset
• Longer interval between maternal RSV vaccination and birth increases placental transfer efficiency July 29, 2024
  CONCLUSIONS: Vaccine administration earlier in the approved 32-36 week window (at least 5 weeks prior to delivery) results in the highest transplacental transfer of maternal antibodies to the neonate. These results should inform the counseling of pregnant individuals on optimal vaccination timing.
  Ms Olyvia J Jasset
• Vaginal microbes alter epithelial transcriptome and induce epigenomic modifications providing insight into mechanisms for susceptibility to adverse reproductive outcomes June 10, 2024
  The cervicovaginal microbiome is highly associated with women's health, with microbial communities dominated by Lactobacillus species considered optimal. Conversely, a lack of lactobacilli and a high abundance of strict and facultative anaerobes, including Gardnerella vaginalis, have been associated with adverse reproductive outcomes. However, how host-microbial interactions alter specific molecular pathways and impact cervical and vaginal […]
  Michal Elovitz